Browsing by Author "Young, Nicole"
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Item Beyond Triptans: A Review of New Migraine Medications in Clinical Trials(2018-04-06) Nakagawa, Christopher; Hino Jr., Garret; Tokumaru, Sheri; Young, Nicole; Tokumaru, Sheri; Young, NicoleMigraines are a very common and debilitating headache disorder characterized by moderate to severe throbbing headache pain, which can be associated with nausea, vomiting, sensitivity to light and sensitivity to sound.This study is a literature review of recent and ongoing clinical trials for new classes of pharmacologic treatments for acute migraine.Item Cost-Effectiveness of Phenytoin and Levetiracetam for Seizure Prophylaxis in Traumatic Brain Injury(2018-04-06) Young, Nicole; Tokumaru, Sheri; Taira, Deborah; Izumi, Kara; Stern, Tracy; Dittrich, Denise; Asai, Susan; Nakagawa, Kazuma; Tokumaru, Sheri; Taira, DeborahSeizures are a potential complication associated with traumatic brain injury (TBI), which can lead to secondary brain injury and increased risk for developing post-traumatic epilepsy. Current guidelines recommend the use of antiepileptic drug (AED) for early seizure prophylaxis in patients with TBI. Both phenytoin (PHE) and levetiracetam (LEV) have become standard of practice for seizure prophylaxis in TBI, yet the cost effectiveness is not well studied.